A wonderful clinical scientist, great friend and mentor to many in the field of respiratory medicine, Frederick E Hargreave (known to everyone as Freddy), died suddenly on 15 June 2011. In the 18th century, the French chemist Antoine-Laurent de Lavoisier conducted breathing experiments on human and animal respiration.
Peripheral blood T cells were also analysed 7 and 30 days after admission. The outbreak is described and the protective effect of BCG vaccination against latent Mycobacterium tuberculosis infection as measured by an interferon gamma release assay (IGRA) is assessed. An audit tool was developed as part of the Guidelines. to sider for example, H-Index, Self-Citation Ratio, SJR (SCImago Journal Rank Indicator) and SNIP (Source Normalized Impact per
Searches were conducted of 10 databases to July 2012 for studies of clinically diagnosed or pathologically confirmed lung cancer associated with household biomass use for cooking and/or heating. Researchers may also consider the practical aspect of a journal such as publication fees, acceptance rate, review speed. We describe the case of a young patient who showed dyspnoea, fever and rapid radiological progression and was simultaneously diagnosed with AEP and 2009 influenza A (H1N1) infection, which was diagnosed by using bronchoalveolar lavage (BAL). Cytokine expression was determined by ELISA in the lungs or BAL fluid.
Co-expression of more than two markers from HIF-1alpha, TWIST1 and Snail is a significant prognostic predictor in patients with NSCLC.Interferon gamma-1b does not improve survival for patients with idiopathic pulmonary fibrosisIdiopathic pulmonary fibrosis (IPF) is characterised by an insidious decline in pulmonary function, progressive worsening symptoms and death, with a median survival of 2–5 years from diagnosis. Subpleural blebs and bullae are found at the lung apices at thoracoscopy and on CT scanning in up to 90% of cases of PSP,5 6 and are thought to play a role. The ORs for lung cancer risk with biomass for cooking and/or heating were OR 1.17 (95% CI 1.01 to 1.37) overall, and 1.15 (95% CI 0.97 to 1.37) for cooking only. Within 4 hours of admission, a chest x-ray was obtained in 83% of patients and the first dose of antibiotics was administered in 58%. Thorax Impact Factor Trend 2000 - 2018 / 2019. A retrospective analysis of 87 patients with resectable NSCLC from Taipei Veterans General Hospital between 2003 and 2004 was performed using immunohistochemistry to analyse HIF-1alpha, TWIST1 and Snail expression. Impact Factor. It will allow the host institutions to benchmark against UK figures and drive quality improvement programmes to promote the quality standard and improve patient care.Year in review 2013: Basic science and epidemiologyIdentification of a systemic molecular signature facilitating early diagnosis and enabling targeted therapy is the Holy Grail for the investigators of many pulmonary diseases, particularly those with heterogeneous presentation such as chronic obstruction pulmonary disease (COPD) or idiopathic pulmonary fibrosis (IPF).
A vaccine effectiveness of 66% was calculated, implying that 21 of the 32 infections could have been avoided if all children had been vaccinated with BCG. Decline was not greater in frequent exacerbator A versus non-A carriers (20 vs 24 ml/year, p=0.58). Upregulation of α(1)-antitrypsin at exacerbation was not demonstrated, even in patients homozygous for the common allele (median exacerbation change -0.07 g/l 11478GG, p=0.87 and -0.09 g/l 11478AA/GA, p=0.92; p=0.90 for difference). Data entry using the web-based audit tool closed in May 2010. The number of submissions remains high; out of 812 total submissions (including letters), 453 were original papers, the highest figure for five years (table 1), and in September we had the highest number submitted …Prognostic significance of hypoxia-inducible factor-1alpha, TWIST1 and SNAIL expression in resectable non-small cell lung cancerMetastasis is the most common cause of disease failure and mortality for non-small cell lung cancer (NSCLC) after surgical resection.